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. 2006 Oct 2;103(41):15050–15055. doi: 10.1073/pnas.0603476103

Fig. 1.

Fig. 1.

Schematic drawing of the active site of WT PYP. The p-coumaric acid chromophore is covalently bound to the protein backbone by means of Cys-69; in addition, it takes part in a distal hydrogen-bonding network. In E46Q, glutamic acid (Glu) is changed to glutamine by using site-directed mutagenesis.