Table 2.
Baseline characteristics of participants by HFE genotype (n = 358).
| HFE wild-type (n = 228) | HFE variant allele (n = 130) | |
|---|---|---|
| Age [median years (IQR)] | 67.2 (62.6–71.8) | 67.7 [63.7–71.3] |
| Education [n (%)] | ||
| Never finished high school | 19 (8.3) | 9 (6.9) |
| High school graduate | 64 (28.1) | 36 (27.7) |
| Some college | 64 (28.1) | 33 (25.4) |
| College graduate | 81 (35.5) | 52 (40.0) |
| Smoking status [n (%)]a | ||
| Never | 76 (33.3) | 46 (35.4) |
| Former | 138 (60.5) | 81 (62.3) |
| Current | 14 (6.1) | 3 (2.3) |
| Alcohol consumption [median g/day (IQR)] | 5.8 [0.4–18.7) | 6.0 [0–16.7) |
| History of diabetesb [n (%)] | 24 (10.5) | 13 (10.0) |
| English as first language [n (%)] | 199 (87.3) | 118 (90.8) |
| Computer experience [n (%)] | 87 (38.2) | 65 (50.0) |
| Patella lead [median μg/g (IQR)] | 24 (15, 37) | 22 (14, 34) |
| Tibia lead [median μg/g (IQR)] | 19.0 (13, 29) | 19.5 (12, 26) |
| Baseline MMSE score [median (IQR)]c | 27 (25, 28) | 27 (26, 28) |
IQR, interquartile range.
a
Percentages may not add up to 100 because of rounding.
b
History of diabetes defined as having reported diagnosis of diabetes or having fasting glucose above 126 mg/dL.
c
Highest possible MMSE score in our analysis was 29 because of deletion of the question “What county are we in?”