Table 4.
Results of multivariablea linear regression by semen outcome, with exposure dichotomized as low (bottom 50th percentile) or high (top 25th percentile) for selected groupings of DBPs.
| Outcomeb | THM4 β (95% CL) | HAA5 β (95% CL) | HAA9 β (95% CL) | THM-Br β (95% CL) | HAA-Br β (95% CL) | TOX β (95% CL) |
|---|---|---|---|---|---|---|
| Sperm countc | 0.35 (−0.02, 0.72) | 0.51 (0.08, 0.93)* | 0.36 (−0.02, 0.75) | −0.06 (−0.44, 0.33) | 0.00 (−0.37, 0.38) | −0.16 (−0.51, 0.19) |
| Sperm concentrationc | −0.16 (−0.49, 0.17) | 0.06 (−0.27, 0.39) | −0.03 (−0.38, 0.31) | −0.23 (−0.54, 0.07) | −0.20 (−0.51, 0.11) | −0.34 (−0.66, −0.03)* |
| Percent normal morphologyd | 0.65 (0.34, 0.96)* | 0.88 (0.55, 1.21)* | 0.67 (0.37, 0.98)* | 0.11 (−0.18, 0.40) | 0.18 (−0.10, 0.47) | 0.04 (−0.24, 0.33) |
| Percent abnormal headd | 0.23 (−0.10, 0.57) | 0.11 (−0.25, 0.47) | 0.28 (−0.06, 0.61) | 0.03 (−0.29, 0.34) | 0.01 (−0.30, 0.33) | 0.20 (−0.12, 0.52) |
| Percent abnormal midsectiond | −0.82 (−1.13, −0.51)* | −0.95 (−1.27, −0.64)* | −0.91 (−1.22, −0.59)* | 0.15 (−0.16, 0.47) | 0.09 (−0.23, 0.41) | 0.10 (−0.24, 0.44) |
| Percent abnormal taild | −1.22 (−1.51, −0.93)* | −1.31 (−1.61, −1.02)* | −1.29 (−1.57, −1.01)* | −0.21 (−0.54, 0.12) | −0.28 (−0.61, 0.04) | −0.28 (−0.60, 0.05) |
| Percent abnormal cytoplasmic dropd | 0.33 (0.02, 0.65)* | 0.31 (−0.02, 0.64) | 0.37 (0.04, 0.70)* | −0.12 (−0.42, 0.18) | −0.10 (−0.41, 0.21) | −0.23 (−0.53, 0.07) |
| Percent CMA | 0.17 (−0.17, 0.50) | −0.04 (−0.38, 0.30) | −0.10 (−0.43, 0.23) | −0.02 (−0.34, 0.31) | −0.01 (−0.34, 0.32) | −0.04 (−0.36, 0.29) |
| Percent DFI | −0.41 (−0.78, −0.05)* | −0.43 (−0.78, 0.08) | −0.51 (−0.85, −0.17)* | −0.15 (−0.49, 0.18) | −0.18 (−0.52, 0.16) | −0.19 (−0.55, 0.16) |
a
All models adjusted for age, days abstaining, and education level.
b
All outcomes standardized such that SD = variance = 1.00.
c
Natural log transformation applied.
d
Arc sine transformation applied.
*
p < 0.05.