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. 2007 Aug 15;2(8):e719. doi: 10.1371/journal.pone.0000719

Table 5. Mean (standard deviation) haematological parameters at screening (the last wash-out cycle) and post-treatment (end of treatment) of the 76 women.

Biochemical Four-Agents-Decoction Placebo
Screening (n = 38) Post-treatment (n = 38) Screening (n = 38) Post-treatment (n = 38)
CA 125, U/mL 17.9 (7.42) 17.0 (9.85) 17.9 (6.63) 16.9 (9.08)
AST, IU/L 18.6 (4.06) 18.3 (3.31) 18.1 (3.76) 19.2 (4.62)
ALT, IU/L 13.2 (5.72) 13.7 (4.78) 12.3 (5.75) 12.4 (4.52)
Uric acid, mg/dL 4.40 (1.32) 4.17 (1.06) 4.40 (1.15) 4.28 (0.97)
Urea nitrogen, mg/dL 10.5 (2.29) 10.9 (2.85) 11.2 (2.31) 11.2 (2.87)
Creatinine, mg/dL 0.79 (0.11) 0.77 (0.08) 0.79 (0.09) 0.80 (0.08)
Lead, µg/L 1.82 (0.78) 2.47 (1.06) 1.39 (0.48) 2.61 (1.06)
Mercury, µg/L 2.29 (1.71) 3.94 (1.72) 3.06 (2.42) 3.71 (1.33)
Arsenic, µg/L 6.89 (3.11) 8.21 (2.94) 7.29 (4.75) 8.36 (3.86)
Copper, µg/L 955.3 (116.0) 994.7 (135.8) 990 (151.9) 1037 (149.7)
Cadmium, µg/L 0.99 (0.38) 1.03 (0.50) 0.94 (0.43) 0.96 (0.50)
Serum Iron, µg/dL 66.1 (37.2) 64.6 (32.8) 74.7 (31.5) 66.0 (30.4)
Hemoglobin, g/dL 12.6 (0.89) 12.4 (1.00) 12.6 (0.85) 12.6 (0.96)
Hematocrit, % 38.8 (2.32) 37.0 (2.42) 38.6 (2.08) 37.3 (2.34)

Regulated limits and actual levels of heavy metals in the study product-FAD: lead<20 ppm, 0.45 ppm; arsenic<5 ppm, 0.14 ppm; cadmium<0.5 ppm, 0.01 ppm; mercury<0.5 ppm, 0.02 ppm.