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. 2007 Jun 6;2007:97125. doi: 10.1155/2007/97125

Figure 1.

Figure 1

Effect of treatment with selective PPARα and PPARδ agonists on BW in lean and DIO AKR/J mice. (a) GW9578, a PPARα agonist (1 mg/kg), GW0742, a PPARδ agonist (30 mg/kg). (b) Filled triangle: GW9578 dosed for 14 days then combined with GW0742; filled diamond: GW0742 dosed for 14 days then combined with GW9578; filled square: GW9578 and GW0742 dosed together for 28 days. The arrow indicates the point at which the sequential combination of PPARα and PPARδ began. Data were analyzed by ANCOVA with repeated measures followed by Dunnett's post hoc test. Values were considered to be significant (*) when a value of P < .05 was achieved. N = 8–10 animals/group.