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. 1998 Mar 3;95(5):2535–2540. doi: 10.1073/pnas.95.5.2535

Figure 3.

Figure 3

Mutant cyclin E proteins cannot overcome a p16 cell cycle block in NIH 3T3 cells. (A) NIH 3T3 cells were transfected with cyclin E in the presence or absence of p16. For each transfected population, DNA content is shown on the x axis and cell number on the y axis. (B) Transient transfection of NIH 3T3 cells comparing in vivo phosphorylation of exogenous large pocket Rb by cyclin E in the presence of exogenous p16.