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VxCxE mutants are defective for Rb but not histone H1 phosphorylation in vitro. (A) Recombinant cyclin E–CDK2 complexes made in baculovirus-infected Sf-9 insect cells were incubated with [γ-32P]ATP and either histone H1 (A) or Rb (B) for increasing amounts of time. Results shown are representative of three different experiments.
