Table 2.
Splenic amyloid deposits induced by treatment with AgNO3 and different synthetic peptide fibrils compared with controls treated with AgNO3 and vehicle or AEF
Treatment | Mice, n | Mice with amyloid | Amyloid grade |
---|---|---|---|
TTR(10–20) | 10 | 1 | 1+ |
TTR(24–35) | 10 | 3 | 1+-3+ |
TTR(105–115) | 10 | 2 | 1+-3+ |
TTR(115–124) | 10 | 5 | 2+ |
IAPP(20–29) | 10 | 2 | 2+ |
AEF | 10 | 10 | 3+-4+ |
Vehicle | 28 | 1 | 1+ |