Figure 1.

Nucleotide and deduced amino acid sequence of hBRCACox. The nucleotide sequence shown is derived from overlapping clones of two different libraries and numbered in 5′ → 3′ direction. Numbers on the left of the sequences indicate the appropriate nucleotide or amino acid position. Nucleotides in the 5′ leader sequence are indicated by negative numbers. The position of the stop codon is indicated by ∗∗∗. The amino acid sequences of tryptic peptides are underlined. Their experimentally determined masses agreed with their calculated masses. In addition, some other peptides could be positioned according to their mass [measured and calculated mass (M+H)⁺ given within parentheses]: amino acids 102–108 (871.2; 871.9), 109–120 (1265.2; 1266.4), 395–409 (1697.9; 1696), and 544–552 (1111.2; 1112.3).