Fig. 3.

The Il12b and Alb1 enhancers contain unmethylated windows. (A) Methylation of the Il12 enhancer and promoter in numerous cell types. Results are diagrammed as in Fig. 1. The ratio values are shown in SI Fig. 8. (B) CpG methylation in the 300-bp Alb1 enhancer in numerous cell types. (C) Results from five bisulfite sequencing experiments in CCE ES cells. The ratio values are shown in SI Fig. 9. (D) DNA sequence of the Alb1 enhancer (−10,566 to −10,865). Transcription factor binding sites are marked above the sequences and CpGs are underlined.