Fig. 5.

ES cells but not thymocytes promote the loss of methylation at a premethylated plasmid. This diagram provides a summary of the results in SI Fig. 14. (A) Methylation profile of the premethylated plasmid before transfection. Colors indicate methylation levels as described in the legend to Fig. 1. (B) Methylation profiles for five ES cell clones transfected with the unmethylated Ptcra enhancer-promoter-reporter plasmid and seven ES cell clones transfected with the premethylated plasmid. (C) Methylation profiles for eight VL3-3M2 clones transfected with the unmethylated plasmid and 20 VL3-3M2 clones transfected with the premethylated plasmid. (D) Methylation profiles for four EL4 clones transfected with the unmethylated plasmid and six EL4 clones transfected with the premethylated plasmid.