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Viremia, CD4+ T cell counts and genotype of replicating virus in macaques exposed weekly intravaginally (A) or intravenously (B) to mixed incoula consisting of 25 TCID50 each of R5 SHIVSF162P3 and X4 SHIVSF33A. Genotype of replicating virus in IVAG and IV infected macaques was determined by real-time PCR. Percentage of circulating X4 virus is shown. + Indicates progression to simian AIDS (SAIDS).
