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. Author manuscript; available in PMC: 2007 Aug 8.
Published in final edited form as: Virology. 2007 Jan 29;362(1):207–216. doi: 10.1016/j.virol.2006.12.024

Table 1.

Culmulative transmission, replication and pathogenesis data from smacaques exposed IVAG to high dose (>3000 TCID50) of different R5 SHIVSF162P3 and X4 SHIVSF33A virus stocks.

Virus Infected/exposed Probability of transmission Peak Viremia Viral setpoint SAIDS/infected Time to SAIDS
R5-SHIVSF162P3 11/13 0.85 105 – 108 102 – 106 6/11 5.5 – 104 weeks
X4-SHIVSF33A 9/16 0.56 106 – 109 102 – 107 7/9 30 – 156 weeks

Results shown are tabulated from contemporaneous study of eight macaques and historic studies in which nine and twelve macaques were exposed IVAG to R5 and X4 SHIV respectively. The historic studies were conducted using different virus stocks and with challenge doses that are equal or greater for the X4 SHIV.