Table 1.
Clinical findings in surgical specimens
| Patient identifier | Patient age (years/sex) | Type of glaucoma | Samples | Duration between surgery and bleb leak | Duration of leakage | Bleb size | IOP (mmHg) | Antimetabolite treatment | Analyses |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 73/M | POAG | Leaking bleb | 56 Months (11/94–7/99) | 3 Months (10/99) | 2+ | 1 (OS) | Yes | G/C, W, I |
| 2 | 77/M | PXFG | Leaking bleb | 41 Months (8/96–01/00) | 3 Months (4/00) | 1+ | 2 (OD) | Yes | I, IZ |
| 3 | 70/M | POAG | Leaking bleb | 44 Months (6/97–1/00) | 7 Months (8/00) | 2+ | 3 (OD) | Yes | G/C, I |
| 4 | 64/F | POAG | Leaking bleb | 42 Months (6/96–12/99) | 3 Months (2/00) | 3+ | 3 (OS) | Yes | I, W |
| 5 | 65/F | PXFG | Leaking bleb | 58 Months (2/95–4/00) | 4 Months (8/00) | 2+ | 5 (OD) | Yes | G/C |
| 6 | 68/F | PXFG | Leaking bleb | 21 Months (3/00) | 19 Months (10/01) | 1+ | 22 (OS) | Yes | G/C, W |
| 7 | 73/F | POAG | Leaking bleb | 78 Months (3/95–9/01) | 3 Months (12/01) | 2+ | 0 (OD) | No | G/C, W |
| 8 | 64/M | Mixed open angle and angle closure glaucoma | Leaking bleb | 6 Months (6/01–12/01) | 3 Months (3/02) | 2+ | 8 (OD) | Yes | G/C |
| 9 | 72/M | POAG | Leaking bleb | 7 Months (8/95–3/96) | 75 Months (6/02) | 1+ | 13 (OS) | Yes | G/C |
| 10 | 87/F | POAG | Leaking bleb | 27 Months (12/99–05/02) | 1 Month (5/02) | 2+ | 3 (OD) | Yes | G/C |
| 11 | 40/M | Inflammatory glaucoma | Leaking bleb | 1 Month, leaking bleb (4/02) | Bleb revision (4/02) | 2+ | 0 (OS) | Yes | G/C |
| 12 | 79/M | CACG | Overhanging bleb | Trab (7/92), leaking (9/92), recovered (10/92), elevated bleb (1/96) | Bleb revision (8/01) | 3+ | 8 (OS) | No | W, G/C |
| 13 | 63/M | POAG | Overhanging bleb | Trab (6/93), elevated bleb (10/98) | Bleb revision (4/00) | 3+ | 14 (OS) | No | I, W, IZ |
| 14 | 55/F | POAG | Overhanging bleb | Trab (6/92), elevated bleb (8/99) | Bleb revision (4/00) | 3+ | 6 (OD) | No | G, C |
| 15 | 74/M | Normal | Aqueous | N/N | N/A | N/A | 20 (OD) | No | G/C |
| 16 | 73/M | POAG | Aqueous | 56 Months (11/94–7/99) | 3 Months (10/99) | 1 (OS) | Yes | G/C, W, I | |
| 17 | 79/M | Normal | Aqueous | N/A | N/A | N/A | 18 (OD) | No | G/C, W |
| 18 | 70/F | Normal | Aqueous | N/A | N/A | N/A | 25 (OD) | No | W |
| 19 | 71/M | Normal | Conjunctiva | N/A | N/A | N/A | 20 (OD) | No | G/C, I |
G/C, gelatin/casein zymography; I, immunohistochemistry; W, western blot analysis; IZ, in situ zymography; N/A, not available; trab, trabeculectomy; POAG, primary open angle glaucoma; PXFG, pseudoexfoliation glaucoma.