Table 3.
Results of two automatic FASTA searches in SDAP that illustrate how to use this site to correctly name a new allergen. While the cedar pollen allergens Jun a 2 and Cry j 2 are very close in sequence (i.e, have a very low expectation (E) value; top table), they are not related to the allergen originally called Jun o 2. This protein, officially named Jun o 4 by the IUIS, is similar to Bet v 4 and other allergens of that sequence family (bottom table).
No | Allergen | Sequence Link in SwissProt/NCBI/PIR | Sequence Length | bit score | E score |
---|---|---|---|---|---|
1 | Jun a 2 | CAC05582 | 507 | 794.0 | 0.0e+00 |
2 | Cry j 2 | P43212 | 514 | 579.2 | 9.5e-167 |
4 | Phl p 13 | CAB42886 | 394 | 198.8 | 2.4e-52 |
No | Allergen | Sequence Link in SwissProt/NCBI/PIR | Sequence Length | bit score | E score |
| |||||
1 | Jun o 4 | O64943 | 165 | 229.0 | 2.7e-62 |
2 | Ole e 8 | Q9M7R0 | 171 | 89.8 | 2.2e-20 |
4 | Syr v 3 | P58171 | 81 | 62.5 | 1.7e-12 |
5 | Bra n 2 | BAA09633 | 82 | 61.3 | 4.0e-12 |
7 | Bra r 2 | Q39406 | 83 | 61.3 | 4.0e-12 |
8 | Aln g 4 | O81701 | 85 | 61.3 | 4.1e-12 |
9 | Bet v 4 | Q39419 | 85 | 60.9 | 5.4e-12 |
11 | Ole e 3 | O81092 | 84 | 59.6 | 1.3e-11 |
12 | Phl p 7 | O82040 | 78 | 58.8 | 2.2e-11 |
15 | Bra n 1 | Q42470 | 79 | 52.8 | 1.4e-09 |
16 | Bra r 1 | Q42470 | 79 | 52.8 | 1.4e-09 |
17 | Bet v 3 | P43187 | 205 | 35.8 | 4.9e-04 |
18 | Gad c 1 | P02622 | 113 | 34.9 | 4.9e-04 |
19 | Sal s 1 | Q91482 | 109 | 33.6 | 1.1e-03 |
20 | Sco j 1 | P59747 | 109 | 31.3 | 5.5e-03 |