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. Author manuscript; available in PMC: 2007 Aug 8.
Published in final edited form as: J Mol Biol. 2006 Jul 31;363(1):137–147. doi: 10.1016/j.jmb.2006.07.063

Figure 3.

Figure 3

The MZF1 SCAN dimer interface.

(a) Strips extracted from a 3D F3-13C-edited NOESY spectrum (left strip) containing both intra- and intermolecular NOEs while strips from the 3D F1-13C-filtered, F3-13C-edited NOESY spectrum (right strip) show only the intermolecular NOEs. Strip pairs are shown for residues L62, L68, L87 and A116. Leucine 68 does not participate in the dimer interface and therefore does not have NOEs in the 3D F1-13C-filtered, F3-13C-edited NOESY spectrum. Box coloring corresponds to the NOEs displayed in panels (c) and (d). (b) Intermolecular contacts at the dimer interface involving residues Q59, L62, V88, P112, E113 and A116. NOE coloring corresponds to the boxed peaks in panel (a). (c) Intermolecular contacts involving residues L73 and L87. NOE coloring corresponds to the boxed peaks in panel (a). (d) Cross-eyed stereo view of the MZF1 SCAN homodimer. Monomers A and B are shown in green and orange, respectively.