Table 5.
Group classifications by hippocampal volume and fractional anisotropy of posterior cingulate
Classification | Factors | Sensitivity (%) |
Specificity (%) |
Accuracy (%) |
p Value* | AUC | p Value† |
---|---|---|---|---|---|---|---|
MCI vs CN | Total HV | 55 ± 8 | 70 ± 5 | 63 ± 3 | 0.1 | 0.67 ± 0.02 | |
TotalHV+LeftPC-FA | 69 ± 3 | 78 ± 2 | 74 ± 2 | 0.02 | 0.78 ± 0.02 | <0.001 | |
AD vs CN | Total HV | 75 ± 3 | 81 ± 3 | 78 ± 1 | 0.007 | 0.85 ± 0.01 | |
TotalHV+LeftPC-FA | 88 ± 1 | 94 ± 2 | 91 ± 1 | <0.001 | 0.98 ± 0.002 | <0.001 |
From logistic regression.
From a Wilcoxon signed rank test, comparing two areas under the curves (AUC).
MCI = mild cognitive impairment; CN = cognitive normal; HV = hippocampal volume; left PC-FA = FA of the left posterior cingulate; AD = Alzheimer disease.