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. 2007 Jul 31;104(32):13128–13133. doi: 10.1073/pnas.0705878104

Fig. 4.

Fig. 4.

Six3 regulation of rhodopsin expression. (A) Rhodopsin IF in retinas from adult WT and MTA1-KO mice. (Inset) Shown are enlargements of stained rhodopsin region. (Right) Quantification of fluorescence density. (B) Northern blot analysis of rhodopsin mRNA (3.5 kb) in retinas from adult WT and MTA1-KO mice. (C) Six3 protein in retinas from adult WT and MTA1-KO mice. (D) Effect of Six3 on the bRho-130 promoter-luc activity in the CV-1 and 293T cells. (E) ChIP of Six3 recruitment onto indicated regions of the murine rhodopsin promoter, using retinas from adult old MTA1-WT (+/+), -heterozygous (+/−), and -homozygous (−/−) mice.