Behavioral effects of SDR in CD-1 mice. Mice were subjected to 6 consecutive days of social disruption (SDR), and behavior was measured on the morning following the 6th day of defeat. (a) In the open field test, defeated mice spent less time in the center of the open field than controls (HCC) and (b) Entered the center of the open field fewer times than controls. (c) Locomotion was not affected by SDR. (d, e) In the forced swim test, CD-1 mice showed no differences in latency to become immobile or in overall time immobile, regardless of defeat treatment. (f) No differences were found in time immobile in the tail suspension test. **p < 0.01