Fig. 5.

Interferon (IFN)-γ elicited from positively selected CD4⁺ lung lymphocytes stimulated in vitro with anti-CD3 and anti-CD28 antibodies, without (hatched bars) and with recombinant murine TGF-β soluble receptor II (TGFβsrII) added to the wells at 5 µg/ml (black bars). There are significant increases in IFN-γ production with TGFβsrII at each time-point: 223% of stimulated value at day 21 (P = 0·02 TGFβsrII versus stimulated (STIM)], 104% of stimulated value at day 28 (P = 0·02 TGFβsrII versus STIM) and 174% of stimulated value at day 35 (P = 0·007 TGFβsrII versus STIM).