Table 2.
Changes in lymphocyte subpopulations.
| Patient | Subset | Pre | 1 m | 4 m | 9 m |
|---|---|---|---|---|---|
| 1 | WBC | 4 100 | 13 400 | 6 400 | 9 200 |
| Lymph | 1 262 | 670 | 2 611 | 5 336 | |
| CD3 | 1 079 | 369 | n.d. | 3 431 | |
| CD4 | 721 | 320 | n.d. | 2 423 | |
| CD45RO+/CD4 (%) | 97·7 | 84·9 | n.d. | 8·7 | |
| CD8 | 345 | 46 | n.d. | 662 | |
| CD45RO+/CD8 (%) | 93·0 | 42·5 | n.d. | 2·6 | |
| CD16 | 92 | 301 | n.d. | 678 | |
| CD20 | 0 | 0 | n.d. | 1 233 | |
| 2 | WBC | 2 800 | 9 800 | 16 000 | 6 900 |
| Lymph | 1 300 | 1 800 | 2 000 | 1 800 | |
| CD3 | 334 | 1 015 | 1 786 | 1 336 | |
| CD4 | 289 | 749 | 1 732 | 1 219 | |
| CD45RO+/CD4 (%) | 97·1 | 79·7 | 98·5 | 71·7 | |
| CD8 | 46 | 202 | 86 | 115 | |
| CD45RO+/CD8 (%) | 44·4 | 51·8 | 64·1 | 56·2 | |
| CD16 | 965 | 718 | 110 | 328 | |
| CD20 | 1 | 2 | 104 | 137 | |
| 3 | WBC | 3 200 | 7 400 | 4 600 | 10 600 |
| Lymph | 512 | 1 110 | 1 242 | 2 600 | |
| CD3 | 73 | 931 | 1 098 | 2 428 | |
| CD4 | 67 | 380 | 452 | 991 | |
| CD45RO+/CD4 (%) | 88·8 | 59·8 | 68·5 | 31·5 | |
| CD8 | 14 | 520 | 653 | 1 446 | |
| CD45RO+/CD8 (%) | 5·9 | 34·9 | 38·5 | 19·6 | |
| CD16 | 440 | 178 | 139 | 122 | |
| CD20 | 0 | 1 | 1 | 10 | |
| 4 | WBC | 26 600 | 8 100 | 7 500 | 10 000 |
| Lymph | 19 600 | 400 | 1 020 | 6 300 | |
| CD3 | 18 855 | 111 | 755 | 3 780 | |
| CD4 | 9 114 | 84 | 609 | 2 905 | |
| CD45RO+/CD4 (%) | 99·8 | 70·2 | 91·5 | 15·9 | |
| CD8 | 10 251 | 27 | 86 | 870 | |
| CD45RO+/CD8 (%) | 99·8 | 72·5 | 71·8 | 2·8 | |
| CD16 | 725 | 289 | 95 | 485 | |
| CD20 | 20 | 0 | 171 | 2 035 |
WBC: white blood cells; n.d.: not done. All lymphocyte numbers represent absolute numbers/μl. CD45RO (%) shows percentages of CD45RO+ cells within each lymphocyte subset.