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The binding characteristics and binding capacities of the native monomeric immunoglobulin A1 (mIgA1) and polymeric IgA1 (pIgA1) to human mesangial cells (HMC). The binding of native mIgA1 and native pIgA1 to HMC was in a dose-dependent and saturable manner. The binding capacity of native pIgA1 was significantly higher than that of native mIgA1 (P < 0·05).
