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. 2007 Aug;149(2):317–326. doi: 10.1111/j.1365-2249.2007.03423.x

Fig. 5.

Fig. 5

Expression of monokine induced by interferon γ (Mig)/CXCL9, interferon-inducible protein-10 (IP-10)/CXCL10 and interferon-inducible T cell α-chemoattractant (I-TAC)/CXCL11 by alveolar macrophages harvested from patients with sarcoidosis. Alveolar macrophages were harvested from healthy volunteers (HV) or patients with sarcoidosis, and cultured without stimulation for 24 or 48 h. The supernatants were harvested, and the concentrations of Mig/CXCL9 (a), IP-10/CXCL10 (b) and I-TAC/CXCL11 (c) were measured with enzyme-linked immunosorbent assay (ELISA). Data are shown as mean ± standard deviation (s.d.). Total RNA was also extracted from alveolar macrophages in HV or patients with sarcoidosis. The real-time quantitative reverse transcription–polymerase chain reactions (RT–PCRs) for Mig/CXCL9 (d), IP-10/CXCL10 (e) and I-TAC/CXCL11 (f) were performed as described in Methods. Data are shown as mean ± s.d. of relative expression compared to β-actin. *P < 0·005 versus HV groups, **P < 0·01 versus HV groups, ***P < 0·05 versus HV groups.