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Osteoprotegerin (OPG) production in human gingival fibroblasts (HGF) stimulated with lipopolysaccharide (LPS). (a) HGF stimulated with 0·01–50 μg/ml of Actinobacillus actinomycetemcomitans ATCC43718 LPS for 24 h. (b) HGF stimulated with 0·01–50 μg/ml of Porphyromonas gingivalis FDC381 LPS for 24 h. OPG in the culture supernatants was measured using enzyme-linked immunosorbent assay. The results are representative of three experiments. **P < 0·01.
