Fig. 2.

Receiver operating characteristic (ROC) curves of anti-neutrophil cytoplasmic antibodies (ANCA) positive vasculitis patients versus healthy controls. Assay sensitivity in comparing ANCA-associated vasculitis (AAV) patients to healthy controls is higher using hypochlorite modified low density lipoprotein (LDL) (grey solid line) and malondialdehyde (MDA) modified LDL (black dotted line) than for copper-modified LDL (black solid line). The latter does not even discriminate between ANCA patients and healthy controls (cf. grey dotted reference line).