Table 1.
(a) Prevalence of anti-platelet (anti-PLTs) and anti-thrombopoietin (anti-TPO) autoantibodies in the sera of lupus patients; (b) post-thrombocytopenic sera do not display autoantibody activity against platelet antigens.
| Antibody | Current | Non-thrombocytopenic | Post-thrombocytopenic | Total |
|---|---|---|---|---|
| (a) | ||||
| Anti-PLTs | 5/11 (45%) | 6/14 (43%) | 0/13 (0%) | 11/38 (29%) |
| Anti-GpIIb/IIIa | 3/11 (27%) | 5/14 (36%) | 0/13 (0%) | 8/38 (21%) |
| Anti-GpIa/IIa | 3/11 (27%) | 4/14 (29%) | 0/13 (0%) | 7/38 (18%) |
| Anti-GpIb/IX | 0/11 (0%) | 2/14 (14%) | 0/13 (0%) | 2/38 (5%) |
| Two or more | 1/11 (9%) | 5/14 (36%) | 0/13 (0%) | 6/38 (16%) |
| Anti-HLA I | 1/11 (9%) | 2/14 (14%) | 0/13 (23%) | 3/38 (8%) |
| Anti-TPO | 4/11 (36%) | 6/14 (43%) | 5/13 (38%) | 15/38 (39%) |
| (b) | Frequency (%) | P-value | ||
| Post-thrombocytopenic versus thrombocytopenic | 0/13 (0%) versus 5/11 (45%) | 0·006 | ||
| Post-thrombocytopenic versus non-thrombocytopenic | 0/13 (0%) versus 6/14 (43%) | 0·007 | ||