Table 2.
Anti-thrombopoietin (anti-TPO)-positive sera have lower TPO concentrations, although unassociated with lower platelet counts.
| Anti-TPO positive | Anti-TPO negative | P-value | |
|---|---|---|---|
| TPO-levels (mean ± s.d.) | 74 pg/ml (± 66) | 147 pg/ml (± 166) | 0·04 |
| Platelets (mean ± s.d.) | 226·2 ± 84·9 × 103/µl | 210·2 ± 116·2 × 103/µl | n.s. |
| Current thrombocytopenic | Non-thrombocytopenic and post-thrombocytopenic | ||
| Anti-TPO-positive | 4/11 | 11/27 | n.s. |
| Current thrombocytopenic and post-thrombocytopenic | Non-thrombocytopenic | ||
| Anti-TPO-positive | 9/24 | 6/14 | n.s. |
| RA | pSS | ||
| TPO levels (mean ± s.d.) | 45·7 ± 35·3 | 49·2 ± 33·5 | 0·02* |
*
Compared to systemic lupus erythematosus (SLE) mean TPO levels (117·3 ± 137·9 pg/ml). pSS: primary Sjögren’s syndrome; RA: rheumatoid arthritis.