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. 2006 Jul;145(1):101–107. doi: 10.1111/j.1365-2249.2006.03094.x

Fig. 1.

Fig. 1

(a) Mean EAE disease scores ± standard error of the mean (SEM) of C57BL/6 mice treated with DMF 5 mg/kg (upright triangle), DMF 15 mg/kg (inverted triangle), MHF (diamond) and carrier alone (square). Preventive treatment was started on day 3. The treatment effect was significant for MHF (P < 0·0001 compared to the control group, two-way anova) and also for DMF, with the 15 mg/kg dose being more effective (P < 0·0001) than the 5 mg/kg dose (P < 0·001). (b) Mean weight and SEM of C57BL/6 mice which were treated with DMF 5 mg/kg (upright triangle), DMF 15 mg/kg (inverted triangle), MHF (diamond) and carrier alone (square) in the experiment shown in (a). DMF 5 mg/kg does not differ much from the control group, whereas the DMF 15 mg/kg group already exhibits lower weight in the beginning. MHF treated animals loose significantly less weight than the control animals (P < 0·001, two-way anova).