Table 3.
Univariate and multivariate associations between clinical characteristics and first day MBL concentrations.
Univariate analysis | Multivariate analysis | |||||||
---|---|---|---|---|---|---|---|---|
Clinical characteristics | n | MBL (µg/ml) Median (IQR) | R | P-value | B | 95% CI | R2 | P-value |
Gestational age | 84 | 0·14 | 0·22 | 0·09 | 0·03–0·14 | 0·49 | 0·004 | |
Birth weight | 84 | 0·06 | 0·62 | |||||
MBL genotype group* | < 0·001 | 0·39 | ||||||
High | 41 | 1·64 (0·98–2·00) | 1 | ; – | – | |||
Medium | 15 | 0·35 (0·11–0·56) | −1·22 | −1·82–0·63 | < 0·001 | |||
Low | 10 | 0·10 (0·05–0·33) | −1·92 | −2·56–1·28 | < 0·001 | |||
Pregnancy-related disease | 0·21 | |||||||
Yes | 22 | 0·66 (0·26–1·56) | ||||||
No | 62 | 1·12 (0·38–1·94) | ||||||
Mode of delivery | 0·43 | |||||||
Vaginal | 33 | 0·77 (0·26–1·89) | ||||||
Caesarean | 51 | 1·10 (0·43–1·89) | ||||||
Maternal fever | 0·10 | |||||||
Yes | 24 | 0·68 (0·16–1·67) | ||||||
No | 60 | 1·12 (0·44–1·97) | ||||||
PROM | 0·43 | |||||||
Yes | 23 | 1·15 (0·47–1·97) | ||||||
No | 61 | 0·77 (0·32–1·89) | ||||||
Antenatal steroid exposure | 0·27 | |||||||
Yes | 37 | 0·84 (0·37–1·64) | ||||||
No | 47 | 0·99 (0·33–1·94) | ||||||
Fetal distress | 0·29 | |||||||
Yes | 42 | 0·79 (0·31–1·56) | ||||||
No | 42 | 1·54 (0·42–1·93) |
MBL2 genotypes of 15 neonates were missing. PROM, prolonged rupture of membranes; IQR, interquartile range; R, Spearman’s rank correlation coefficient; B, regression coefficient; 95% CI, 95% confidence interval
R2, Adjusted cumulative explained variance.