Table 3.
Correlations between plasma cytokine and chemokine concentrations with urine albumin : creatinine ratio in type 2 diabetes mellitus (DM) patients.
| Cytokine | Group | Spearman's r | P-value |
|---|---|---|---|
| TNF-α | NDN | n.a. | n.a. |
| DN | 0·296 | 0·046* | |
| NDN + DN | n.a. | n.a. | |
| IL-6 | NDN | 0·301 | 0·163 |
| DN | 0·280 | 0·038* | |
| NDN + DN | 0·239 | 0·038* | |
| IL-10 | NDN | 0·291 | 0·149 |
| DN | 0·276 | 0·040* | |
| NDN + DN | 0·255 | 0·016* | |
| IL-18 | NDN | −0·074 | 0·786 |
| DN | 0·273 | 0·027* | |
| NDN + DN | 0·361 | 0·000*** | |
| Adiponectin | NDN | −0·333 | 0·385 |
| DN | 0·287 | 0·048* | |
| NDN + DN | 0·256 | 0·035* | |
| CXCL8 | NDN | −0·170 | 0·473 |
| DN | 0·278 | 0·042* | |
| NDN + DN | 0·247 | 0·029* | |
| CXCL9 | NDN | 0·012 | 0·9504 |
| DN | 0·245 | 0·049* | |
| NDN + DN | 0·352 | 0·001*** | |
| CXCL10 | NDN | 0·274 | 0·159 |
| DN | 0·318 | 0·009** | |
| NDN + DN | 0·381 | 0·000*** | |
| CCL2 | NDN | −0·176 | 0·370 |
| DN | 0·271 | 0·031* | |
| NDN + DN | 0·313 | 0·002** | |
| CCL5 | NDN | 0·192 | 0·328 |
| DN | 0·125 | 0·328 | |
| NDN + DN | 0·274 | 0·009** |
Results are expressed as correlation coefficient r
*
P < 0·05
**
P < 0·01
***
P < 0·001. n.a.: Not calculated due to below detection limit of plasma tumour necrosis factor (TNF)- α concentrations. IL: interleukin; NDN: diabetic nephropathy; DN: diabetic nephropathy.