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Renal impairment and alteration of Fas-, Bcl-2 proteins in lupus nephritis.
| Aspect | Control | Lupus nephritis | P-value |
|---|---|---|---|
| Creatinine clearance | 104 ± 1·0 | 103·3 ± 1·7 | 0·05 |
| β2M (ug/ml) | 0·2 ± 0·1 | 4·2 ± 1·9 | < 0·000 |
| 24 h protein in urine g/24 h | 0·5 ± 0·1 | 1·7 ± 0·5 | < 0·000 |
| Serum Bcl-2 (ng/ml) | 148·6 ± 87 | 217·1 ± 85·9 | < 0·05 |
| Serum Fas (pg/ml) | 550·3 ± 91 | 767·9 ± 271 | < 0·05 |
| Bcl 2 (+) cell/glomerulus | 0·0 ± 0·0 | 1·3 ± 0·1 | < 0·000 |
| Fas (+) cell/glomerulus | 0·0 ± 0·0 | 2·0 ± 0·1 | < 0·000 |
