Table 1.

Inflammatory cell infiltration in experimental autoimmune MG (EAMG) muscle.

Rat group	Inflammatory score	ED1+ cells per field
Naive (n = 1)	0	< 10
w-t; EAMG (n = 6)	3·5 ± 0·55	120 ± 35
C6d; EAMG (n = 6)	0·5 ± 0·22	19 ± 12
C6d/C6; EAMG (n = 6)	3·2 ± 0·48	135 ± 24

EAMG was induced in wild-type (w-t), C6-deficient (C6d) and C6-deficient administered C6 (10 mg/kg at time 0 and 12 h; C6d/C6) rats. Inflammation in muscle was assessed in two ways. Inflammatory infiltrates in haematoxylin and eosin-stained sections were assessed in a semiquantitative manner and scored blind on a scale from 0, no inflammatory infiltrates; 1, infiltrates < 1 per low power field; 2, infiltrates 1–5 per field; 3, infiltrates 6–10 per field; 4, infiltrates > 10 per field. Scores represent means for the stated groups ± s.d. Infiltration of ED1⁺ cells was measured in frozen sections by staining with specific antibody. Positive cells were counted in three sections per animal to obtain mean scores. Numbers shown represent mean of these means for each experimental group ± s.d.