Table 2.
Interferon (IFN)-γ concentration in culture supernatants by coronary artery disease (CAD), Chlamydia status and Helicobacter pylori status.
| IFN-γ (pg/ml) (no added C.pn antigen) | IFN-γ (pg/ml) (C.pn antigen 10 µg/ml) | ||||
|---|---|---|---|---|---|
| n | Median (95% CI) | P* | Median (95% CI) | P* | |
| CAD | |||||
| None/mild | 50 | 2·3 (0, 10·0) | 20·8 (1·5, 40·3) | ||
| Moderate | 51 | 0 (0, 5·4) | 15·5 (4·5, 46·5) | ||
| Severe | 38 | 0·5 (0, 5·8) | 0·598 | 15·3 (3·4, 25·4) | 0·913 |
| Chlamydia status | |||||
| Seropositive | 42 | 5·2 (0, 8·4) | 22·5 (9·0, 51·7) | ||
| Seronegative | 97 | 0 (0, 2·4) | 0·098 | 14·4 (3·1, 24·7) | 0·102 |
| H. pylori status | |||||
| Seropositive | 38 | 0 (0, 0) | 2·4 (0, 12·7) | ||
| Seronegative | 101 | 3·0 (0, 6·0) | 0·005 | 24·9 (15·0, 39·8) | 0·004 |
Results are expressed as medians and 95% confidence intervals.
*
The non-parametric Kruskal–Wallis test was used to compare IFN-γ-value across the CAD groups; Z-value from rank sum test was used for Chlamydia groups and H. pylori groups.