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. 2007 Aug 22;2(8):e768. doi: 10.1371/journal.pone.0000768

Table 1. Genes changed by NA10 and ND13 but not by the ND13(N51S) mutant compared to the GFP control.

Gene name and description Accession # ND13 fold change ANOVA p-value NA10 fold change ANOVA p-value Biological process
Crisp1, cysteine-rich secretory protein 1 NM_009638 18.3 6.04E-06 30.8 7.92E-06 Unknown
Nr4a1, nuclear receptor subfamily 4, group A, member 1 NM_010444 8.1 2.90E-02 1.8 5.70E-03 Transcription
Igh-6, immunoglobulin heavy chain 6 (heavy chain of IgM) BB226392 5.0 2.90E-03 3.2 3.81E-05 Signal transduction/Immune response/Cell proliferation
Ptprf, protein tyrosine phosphatase, receptor type, F BF235516 4.5 3.69E-03 1.8 1.10E-03 Signal transduction
Pdcd1lg2, programmed cell death 1 ligand 2 NM_021396 4.1 3.79E-05 2.0 2.42E-03 Cell proliferation
Pbx3, pre B-cell leukemia transcription factor 3 NM_016768 3.9 6.23E-06 4.8 1.19E-05 Transcription/Development
Hlf, hepatic leukemia factor NM_172563 3.4 3.52E-02 6.8 4.03E-04 Transcription/Cell proliferation
Ahr, aryl-hydrocarbon receptor NM_013464 3.4 2.54E-03 3.1 2.35E-05 Transcription/Signal transduction
Hlx1, H2.0-like homeo box 1 NM_008250 3.4 3.99E-03 1.8 4.96E-03 Transcription
Ier3, immediate early response 3 NM_133662 3.3 9.35E-04 1.5 8.00E-03 Unknown
Erbb2ip, Erbb2 interacting protein BM240030 3.3 9.17E-04 2.3 1.21E-03 Signal transduction
Tmem71, transmembrane protein 71 AV173260 3.0 4.03E-05 2.5 4.65E-05 Unknown
Pkp2, plakophilin 2 AA516617 3.0 7.13E-06 1.7 1.48E-03 Cell adhesion/Development
Pira1, paired-Ig-like receptor A1 NM_011093 3.0 1.56E-02 2.3 2.13E-02 Cell cycle/Immune response
Tgm2, transglutaminase 2, C polypeptide BB041811 2.9 2.99E-03 2.9 3.04E-03 Signal transduction/Metabolism/Cell adhesion
Lilrb3, leukocyte immunoglobulin-like receptor, subfamily B, member 3 U96693 2.8 5.50E-03 2.0 8.22E-04 Cell cycle/Immune response
Cables1, Cdk5 and Abl enzyme substrate 1 AF328140 2.8 2.87E-03 1.8 2.59E-02 Cell cycle/Development
H2-DMa, histocompatibility 2, class II, locus DMa NM_010386 2.8 7.61E-03 2.2 1.74E-02 Immune response/Transport
Ahrr, aryl-hydrocarbon receptor repressor NM_009644 2.7 9.31E-04 2.2 2.48E-03 Signal transduction/Transcription/Metabolism
Fads3, fatty acid desaturase 3 BE652876 2.7 1.07E-02 1.9 7.20E-03 Metabolism
Tspan6, tetraspanin 6 NM_019656 2.7 1.14E-04 1.7 2.10E-03 Unknown
Tmem51, transmembrane protein 51 BC003277 2.7 5.61E-03 2.1 3.87E-03 Unknown
Rab4a, RAB4A, member RAS oncogene family NM_009003 2.6 1.41E-03 3.4 1.40E-04 Transport/Signal transduction
Anxa1, annexin A1 NM_010730 2.5 3.65E-03 2.4 4.42E-03 Cell cycle/Cell proliferation/Signal transduction
Pscdbp, pleckstrin homology, Sec7 and coiled-coil domains, binding protein BC007144 2.4 3.04E-03 1.6 4.34E-02 Cell adhesion
F2rl2, coagulation factor II (thrombin) receptor-like 2 NM_010170 2.4 8.34E-04 2.2 9.01E-04 Coagulation/Signal transduction
RIKEN cDNA C230093N12 gene BC023470 2.4 2.04E-03 1.5 1.70E-02 Unknown
Cish, cytokine inducible SH2-containing protein NM_009895 2.4 6.78E-04 1.6 3.19E-02 Cell growth/Signal transduction
Tsc22d1, TSC22 domain family, member 1 BB357514 2.4 2.60E-03 2.0 7.37E-03 Transcription
Wdfy2, WD repeat and FYVE domain containing 2 BB794924 2.4 6.33E-03 1.7 6.51E-03 Unknown
Pld3, phospholipase D family, member 3 NM_011116 2.3 8.47E-03 2.6 4.39E-05 Metabolism
Dnase1l1, deoxyribonuclease 1-like 1 AK009174 2.3 1.84E-02 1.9 2.87E-02 Metabolism
Mylc2pl, myosin light chain 2, precursor lymphocyte-specific NM_021611 2.3 2.35E-02 2.9 1.82E-03 Unknown
RIKEN cDNA 1700027N10 gene BC019423 2.3 4.46E-04 2.2 8.76E-04 Unknown
Cyp4f16, cytochrome P450, family 4, subfamily f, polypeptide 16 NM_024442 2.3 5.32E-04 1.9 2.91E-03 Transport
Hoxa5, homeo box A5 BC011063 2.3 7.95E-04 3.9 3.02E-05 Transcription/Development
Crisp3, cysteine-rich secretory protein 3 NM_009639 2.2 1.20E-04 2.1 3.50E-02 Unknown
Procr, protein C receptor, endothelial NM_011171 2.2 8.99E-03 2.5 5.25E-05 Coagulation
Plek, pleckstrin AF181829 2.2 5.53E-03 1.8 1.44E-02 Signal transduction
Mitf, microphthalmia-associated transcription factor BB763517 2.2 9.81E-03 1.9 2.58E-03 Development/Transcription
Metrnl, meteorin, glial cell differentiation regulator-like BC024445 2.1 2.00E-02 2.2 1.79E-02 Unknown
Prnp, prion protein BE630020 2.1 2.13E-03 2.3 8.29E-03 Metabolism
Sord, sorbitol dehydrogenase AV253518 2.1 1.49E-02 2.3 5.31E-04 Unknown
Rpgrip1, retinitis pigmentosa GTPase regulator interacting protein 1 AK015037 2.1 1.98E-04 1.6 3.35E-03 Development
Gsn, gelsolin NM_010354 2.1 8.22E-03 2.1 2.22E-02 Transport
Hoxa7, homeo box A7 NM_010455 2.0 2.45E-02 1.7 2.38E-02 Transcription/Development
Mef2c, myocyte enhancer factor 2C AI595932 2.0 2.58E-02 1.7 6.06E-03 Transcription/Development
Eltd1, EGF, latrophilin seven transmembrane domain containing 1 BC017134 2.0 2.94E-04 1.9 4.89E-04 Signal transduction
Flt3, FMS-like tyrosine kinase 3 NM_010229 2.0 2.44E-02 2.0 2.32E-02 Signal transduction/Development
Ncoa1, nuclear receptor coactivator 1 NM_010881 1.9 2.24E-02 1.5 6.81E-03 Transcription/Signal transduction
Ddx4, DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 AK014844 1.9 2.04E-03 13.3 1.92E-06 Development
Calcrl, calcitonin receptor-like AF209905 1.9 1.37E-02 1.8 1.97E-02 Cell proliferation/Signal transduction/Development
St8sia4, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 NM_009183 1.9 1.87E-03 2.0 1.77E-03 Metabolism
Glul, glutamate-ammonia ligase AI391218 1.9 1.09E-02 1.7 1.64E-02 Metabolism
Lrp10, low-density lipoprotein receptor-related protein 10 BC011058 1.9 3.27E-03 1.8 5.96E-03 Metabolism/Transport
Hoxa9, homeo box A9 NM_010456 1.8 1.06E-02 2.5 1.33E-03 Transcription/Development
Malat1, metastasis associated lung adenocarcinoma transcript 1 AW012617 1.8 3.31E-02 1.9 1.27E-03 Unknown
Ptk2b, PTK2 protein tyrosine kinase 2 beta AV026976 1.8 8.99E-03 1.7 1.34E-02 Signal transduction
Igfbp7, insulin-like growth factor binding protein 7 AI481026 1.8 1.25E-02 1.7 2.41E-02 Cell growth/Metabolism
Mxd4, Max dimerization protein 4 BG868949 1.8 1.23E-02 1.8 7.84E-03 Transcription
Sesn1, sestrin 1 BG076140 1.8 1.60E-03 1.8 1.42E-03 Cell cycle
Itm2c, integral membrane protein 2C NM_022417 1.8 3.67E-03 1.5 2.97E-02 Unknown
RIKEN cDNA 4930504E06 gene BB010153 1.7 2.71E-02 1.8 2.82E-03 Unknown
Man1a, mannosidase 1, alpha NM_008548 1.7 9.38E-03 1.6 1.53E-02 Metabolism
Aldoc, aldolase 3, C isoform BC008184 1.7 2.36E-02 1.8 2.93E-02 Metabolism
Cln3, ceroid lipofuscinosis, neuronal 3, juvenile NM_009907 1.7 4.55E-03 1.7 5.18E-03 Unknown
Arrb1, arrestin, beta 1 AK004614 1.7 6.77E-03 1.8 7.22E-03 Signal transduction
Cast, calpastatin AB026997 1.7 8.19E-03 1.8 2.99E-03 Metabolism
Nupr1, nuclear protein 1 NM_019738 1.7 4.92E-03 2.0 8.18E-03 Unknown
Jag2, jagged 2 AV264681 1.7 2.21E-02 1.6 1.15E-02 Signal transduction/Development/Cell proliferation
Bckdha, branched chain ketoacid dehydrogenase E1, alpha polypeptide NM_007533 1.6 3.33E-02 1.8 1.30E-02 Metabolism/Transcription
Prkcn, protein kinase C, nu BF160591 1.6 1.17E-02 1.7 3.48E-03 Signal transduction
Pnp, purine-nucleoside phosphorylase AK008143 1.5 3.02E-03 1.5 2.90E-02 Metabolism
Tcf4, transcription factor 4 AI639846 1.5 2.96E-02 1.5 1.42E-02 Transcription/Development