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. 2007 Aug 22;2(8):e761. doi: 10.1371/journal.pone.0000761

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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The 3D model was generated by averaging 10,000 instantaneous structures obtained at 1.0-ps intervals during the last 0.5-ns period of 20 molecular dynamics simulations (2.0 ns for each simulation with a 1.0-fs time step and a unique seed for initial velocities) followed by 200 steps of energy minimization of the average structure of the entire complex.