Table 1.
Absolute binding of [125I]iodosulpride in the striatum of restricted-fed and ad libitum-fed rats.
Feeding conditions | Striatal regions | ||
---|---|---|---|
Restricted feeding | NAcc core | NAcc shell | Dorsolateral striatum |
Contingent sucrose-food (CSF; n= 6) | 5.80 ± 0.25 | 6.54 ± 0.36 | 9.52 ± 0.37 |
Non-contingent sucrose-food (NCSF; n= 6) | 5.99 ± 0.19 | 6.82 ± 0.17 | 11.70 ± 0.28* |
Contingent food-food (CFF; n= 6) | 6.08 ± 0.21 | 7.40 ± 0.50* | 10.78 ± 0.34 |
Ad libitum feeding | |||
Naive (n= 6) | 5.80 ± 0.26 | 5.90 ± 0.36 | 10.21 ± 0.23 |
Binding is expressed in fmol/mg tissue equivalent ± SEM. Autoradiography binding was performed on striatal sections (AP:1.7–1.1mm from Bregma) on day 7 of the feeding regimen (see Materials and methods for details). Statistical comparisons of restricted fed groups to ad libitum fed groups are indicated
p<0.01 and p<0.05. For binding differences between groups within striatal structures see Fig. 1.