TABLE 6. Gene Expression Profiles in Control Brain Regions: Apoptosis-Related.
Protein encoded | Gene | Genbank | Brainstem | Forebrain |
---|---|---|---|---|
B-cell leukemia/lymphoma 2 | bcl2 | AF149299 | 0.96 ± 0.04 | 1.02 ± 0.03 |
bcl2-associated death promoter | bad | NM022698 | 0.80 ± 0.04 | 1.23 ± 0.04* |
bcl2-associated athanogene 1 | bag1 | XM216377 | 0.96 ± 0.02 | 1.20 ± 0.04* |
bcl2 antagonist/killer 1 | bak1 | NM053812 | 1.06 ± 0.02 | 0.99 ± 0.04 |
bcl2-associated X-protein | bax | AF235993 | 0.93 ± 0.01 | 1.10 ± 0.03* |
bcl2-associated transcription factor 1 | bclaf1 | XM214967 | 0.73 ± 0.07 | 1.27 ± 0.02* |
bcl2 modifying factor | bmf | NM139258 | 1.14 ± 0.06 | 0.98 ± 0.05 |
caspase 1 | casp1 | NM012762 | 1.25 ± 0.08 | 0.96 ± 0.10 |
caspase 2 | casp2 | NM022522 | 0.83 ± 0.02 | 1.07 ± 0.03* |
caspase 3 | casp3 | NM012922 | 0.83 ± 0.03 | 1.35 ± 0.02* |
caspase 4 | casp4 | NM053736 | 1.39 ± 0.04* | 0.82 ± 0.04 |
caspase 6 | casp6 | NM031775 | 1.43 ± 0.12* | 0.88 ± 0.03 |
caspase 7 | casp7 | NM022260 | 1.25 ± 0.04* | 0.82 ± 0.02 |
caspase 9 | casp9 | NM031632 | 0.84 ± 0.01 | 0.99 ± 0.03* |
caspase 12 | casp12 | NM130422 | 1.04 ± 0.04* | 0.90 ± 0.02 |
apoptosis-related caspase activation inhibitor | aven | XM230438 | 1.01 ± 0.04 | 1.03 ± 0.03 |
tumor protein 53 (p53) | tp53 | NM030989 | 0.83 ± 0.08 | 0.88 ± 0.16 |
Significantly higher than in the other region.