Fig. 2.
COX-1 and COX-2 mRNA expression in the hippocampi (A-B) of 4, 12, 24 and 30 month-old F344 rats. Data (mean ± SEM, n=5–6) are normalized to the level of the internal control, GAPDH and are expressed as the percentage of the 4 month-old rats. p values are expressed as the comparison of aged rats with 4-month-old rats using One-Way ANOVA (*p<0.05, ***p<0.001; post-hoc Bonferroni test).