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. Author manuscript; available in PMC: 2007 Aug 13.
Published in final edited form as: Brain Res Bull. 2007 Mar 20;73(1-3):108–113. doi: 10.1016/j.brainresbull.2007.02.015

Table 1.

mRNA expression of genes involved in the PLA2/COX pathway in the rat cerebral cortex during aging using quantitative real–time PCR.

Genes1 4 months (n=6) 12 months (n=6) 24 months (n=6) 30 months (n=5)
COX-1 100 ± 2 100 ± 5 105 ± 9 108 ±7
COX-2 100 ± 5 126 ±12 100 ± 3 97 ± 8
cPLA2 101 ± 5 113 ± 6 118 ± 6 105 ± 7
iPLA2 100 ± 3 96 ± 4 90 ± 6 88 ± 6
GFAP 101 ± 6 122 ± 4 206 ± 12 *** 241 ± 11 ***
1

Data (mean ± SEM, n=5–6) are normalized to the level of the internal control, GAPDH, and are expressed as the percentage of values in the 4 month-old rats. p values are expressed as the comparison of aged rats with 4-month-old rats using One-Way ANOVA

***

p<0.01; post-hoc Bonferroni test.