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. Author manuscript; available in PMC: 2008 Jul 18.
Published in final edited form as: Cancer Lett. 2007 Feb 14;252(2):299–306. doi: 10.1016/j.canlet.2007.01.001

Fig.3.

Fig.3

Inhibition of AR prevents TNF-α -induced NF-κB activation in Caco-2 cells. Growth-arrested Caco-2 cells were pre-incubated with or without sorbinil or tolrestat 20 μM for 24 h and transiently transfected with pNF-κB secretary alkaline phosphatase construct and control plasmid, pTALSEAP and measured alkaline phosphatase (SEAP) activity as described in methods. The Inset in D shows the chemiluminescence of SEAP detected with Kodak Image Station 2000R. Bars represent mean ± S.E. (n = 4); #, p < 0.001 as compared to control cells. *, p < 0.001 compared to cells treated with TNF-α alone.