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. Author manuscript; available in PMC: 2007 Aug 13.
Published in final edited form as: Virology. 2007 Apr 16;362(1):235–244. doi: 10.1016/j.virol.2007.02.033

Figure 6. Weight loss, morbidity and MV infection levels in untreated and aprepitant-treated NSE-CD46+/RAG-2 KO mice.

Figure 6

Figure 6

(A) Mice were infected as described and administered aprepitant orally one day prior to infection (double dose), one day after infection, and every other day thereafter. Mice were monitored daily, and scored from 0-4, based on the defined criteria (see Materials and Methods). Average values (obtained between days 6 and 10) are shown. Mice were also weighed on the day before infection to establish individual baselines, and every other day thereafter. Maximal weight changes are shown as percent weight loss or gain. (B) Mice were infected as described, and collected between 10-12 days post-infection. Shown are immunohistochemical results from untreated (a-c) and aprepitant-treated (d-i) mice. (d-f): sick animals at collection; (g-i): healthy animals at collection. Original magnification=20X.