Table I.
Descriptive Statistics for Prostate Cancer Cohorts in Finland
| Description | Cohort-1 | Cohort-2 | Combined Cohorts |
|---|---|---|---|
| Probands | 557 | 989 | 1,546 |
| Non-probands | 3,631 | 7,019 | 10,650 |
| Affected non-probands | 51 | 109 | 160 |
| Number of affected | 608 | 1,098 | 1,706 |
| Individuals in cohort | 4,188 | 8,008 | 12,196 |
| Number of Males | 2,418 (57.7%) | 4,664 (58.2%) | 7,082 (58.1%) |
| Number of Females | 1,770 (42,3%) | 3,344 (46.9%) | 5,114 (41.9%) |
| Number of Fathers | 390 | 673 | 1,063 |
| Number of Brothers | 846 | 1,840 | 2,686 |
| Number of Sons | 625 | 1,162 | 1,787 |
| Number of Mothers | 388 | 681 | 1,069 |
| Number of Sisters | 794 | 1,642 | 2,436 |
| Number of Daughters | 588 | 1,021 | 1,609 |
| Mean age of probands (years) | 56.6 ± 3.4 | 74.4 ± 7.4 | 68.2 ±10.7 |
| Range of age at diagnosis of probands (years) | 41.8 – 60.9 | 61 – 96 | 41.8 – 96 |
| Mean age of affected non-probands (years) | 69.6 ± 8.0 | 71.9 ± 7.8 | 71.2 ± 7.9 |
| Range of age at diagnosis of affected non-probands (years) | 48.3 – 85.5 | 48.1 – 88.7 | 48.1 – 88.7 |
| Unaffected men aged ≥ 48 (years) | 909 (18.3%) | 2,141 (23.0%) | 3,050 (21.4%) |
| Mean age of unaffected men (years) | 65.2 ± 9.8 | 67.5 ± 12.3 | 66.6 ± 11.4 |
| Range of ages of unaffected men (years) | 48 – 85.5 | 48 – 104.3 | 48 –104.3 |
| Pedigree sizes (average; range) | 8.9 (3–23) | 9.4 (3–25) | 9.2 (3–25) |
| Percent of pedigrees with ≥ 10 and ≥20 persons | 28% (0.7%) | 37.6% (0.5%) | 34.2% (0.6%) |