Amino acid sequence comparison of Arabidopsis CRY2, CRY1, and E. coli DNA photolyase (PHR). The optimal alignment was obtained by using the MACAW program. Identical residues in all three sequences are boxed; identical residues conserved in CRY2 and CRY1 are underlined; residues of the E. coli photolyase involving in the binding of folate (•), flavin (▪), and the DNA substrate (▴), are indicated.