Table 6.

Prediction accuracies for the three data sets shown in Table 1

Data set	Prediction accuracy,* %†				Prediction accuracy,* % assuming all hydrophobic residues are buried
	≥95% burial	≥90% burial	≥80%‡ burial	≥80%§ burial	≥95% burial	≥90% burial	≥80% burial
Original	80	80	84	78	52	62	75
Test1	100	60	75	89	46	54	69
Test2	None found	100	83	100	44	52	65

Buried residues in each data set are predicted using the criteria in Table 4 and the accuracies are calculated from the percentage of predicted residues that are actually buried in the protein crystal structure. 

^*Percent accuracy = 100% (number of predicted buried residues actually buried)/(total number of predicted buried residues). 

^†Using criteria from Table 4. 

^‡Based solely on H_av criteria. 

^§Based solely on H_mom criteria.