Abstract
Clindamycin was given orally over prolonged periods to 12 patients with chronic osteomyelitis. It was well tolerated with only minor side effects and no major toxicity. Clinical and bacteriological cure occurred in five patients and improvement was noted in another five. It appears less effective than either lincomycin or cloxacillin but, because of the complex nature of both the disease and its treatment, strict comparisons are very difficult.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Allergic alveolitis. Br Med J. 1970 Mar 21;1(5698):708–708. [PMC free article] [PubMed] [Google Scholar]
- Bell S. M. Oral penicillins in the treatment of chronic staphylococcal osteomyelitis. Lancet. 1968 Aug 10;2(7563):295–297. doi: 10.1016/s0140-6736(68)90520-5. [DOI] [PubMed] [Google Scholar]
- Hnatko S. I. The treatment of acute and chronic staphylococcal osteomyelitis and soft tissue infections with lincomycin. Can Med Assoc J. 1967 Sep 9;97(11):580–584. [PMC free article] [PubMed] [Google Scholar]
- Stiver H. G., Ronald A. R. Clinical and laboratory experience with clindamycin. Antimicrob Agents Chemother (Bethesda) 1970;10:481–485. [PubMed] [Google Scholar]
