Table 1.

Percentage blood glucose reduction produced by C. roseus after oral administration in normal rabbits.

Group (n = 5)	Dose	Initial Blood glucose (mg/dl)	Percent blood glucose reduction
			4	6	8	10	12	16	18	20	24 (h)
Control	---	105.6	-3.1 ± 5.3	-2.4 ± 6.4	-0.4 ± 6.2	-3.6 ± 5.0	-6.9 ± 6.3	-4.5 ± 4.2	-0.4 ± 9.9	5.9 ± 1.5	-1.5 ± 4.6
C. roseus	0.50 ml/kg	99.2	11.5 ± 0.7*	16.7 ± 1.2*	15.3 ± 3.1	12.6 ± 2.4*	4.9 ± 8.0	4.6 ± 6.6	8.1 ± 2.1	8.9 ± 1.9	1.0 ± 4.4
C. roseus	0.75 ml/kg	101.4	13.9 ± 5.1*	17.1 ± 1.9*	19.5 ± 3.4*	19.7 ± 5.7*	22.8 ± 3.1**	27.0 ± 0.7***	28.6 ± 0.4*	14.7 ± 6.2	4.3 ± 7.1
C. roseus	1.0 ml/kg	108.5	14.1 ± 3.3*	17.5 ± 3.2*	19.2 ± 2.6*	20.8 ± 6.1*	24.4 ± 4.4**	29.6 ± 4.2***	30.7 ± 5.2*	31.9 ± 5.3**	30.0 ± 1.4***
Glibenclamide	40 μg/kg	104.2	25.5 ± 4.1**	29.7 ± 4.9**	31.9 ± 4.8**	29.8 ± 5.2**	28.3 ± 4.7**	23.1 ± 3.6**	21.9 ± 3.6	19.8 ± 5.4	17.3 ± 4.7

Values are mean percent blood glucose reduction (± S.E.M.) of five animals. Significant difference from control at corresponding intervals: *p < 0.05, **p < 0.01, ***p < 0.001