Table 3.
Allele and genotype frequencies of dopamine receptor polymorphisms in patient and control groups.
| Locus | Genotype Frequency | χ2 | P | Allele Frequency | χ2 | P | |||
| Taq1B (rs 1079597) | B1B1 | B1B2 | B2B2 | 2.0 | 0.36 | B1 | B2 | 0.03 | 0.86 |
| Cases (n = 212) | 0.05(11) | 0.41(86) | 0.54(115) | 0.25(108) | 0.75(316) | ||||
| Controls (n = 196) | 0.08(16) | 0.36(70) | 0.56(110) | 0.26(102) | 0.74(290) | ||||
| Taq1D (rs 1800498) | D1D1 | D1D2 | D2D2 | 2.49 | 0.29 | D1 | D2 | 0.004 | 0.95 |
| Cases (n = 211) | 0.12(25) | 0.58(123) | 0.30(63) | 0.41(173) | 0.59(249) | ||||
| Controls (n = 195) | 0.15(30) | 0.51(99) | 0.34(66) | 0.41(159) | 0.59(231) | ||||
| S311C (rs 1801028) | GG | GC | CC | 0.41 | 0.81 | G | C | 0.01 | 0.92 |
| Cases (n = 210) | 0.80(169) | 0.18(38) | 0.10(3) | 0.89(376) | 0.11(44) | ||||
| Controls (n = 195) | 0.81(159) | 0.16(32) | 0.02(4) | 0.90(350) | 0.10(40) | ||||
| H313H1 (rs 6275) | TT | TC | CC | 9.60 | 0.008* | T | C | 2.92 | 0.09 |
| Cases (n = 213) | 0.36(76) | 0.43(92) | 0.21(45) | 0.57(244) | 0.43(182) | ||||
| Controls (n = 193) | 0.23(44) | 0.57(110) | 0.20(39) | 0.51(198) | 0.49(188) | ||||
| Taq1A2 (rs 1800497) | A1A1 | A1A2 | A2A2 | 4.88 | 0.09 | A1 | A2 | 0.57 | 0.45 |
| Cases (n = 212) | 0.08(17) | 0.44(93) | 0.48(102) | 0.30(127) | 0.70(297) | ||||
| Controls (n = 194) | 0.15(29) | 0.40(77) | 0.45(88) | 0.35(135) | 0.65(253) | ||||
1H313H dominant model (TT Vs TC+CC) P = 0.0045, Odds = 1.879, CI = 1.212 to 2.911
2 Taq1A recessive model (A1A1 Vs A1A2+A2A2) P = 0.029, Odds = 0.4960, CI = 0.2632 to 0.9348