Table 5.

Allele and genotype frequencies of dopamine receptor polymorphism in responder and non responder groups in patient population based on percent response score ≤ 50% ≥.

Locus	Genotype Frequency			χ2	P	Allele Frequency		χ2	P
Taq1B (rs 1079597)	B1B1	B1B2	B2B2	0.18	0.915	B1	B2	0.15	0.7
Responders(n = 121)	0.04(5)	0.42(51)	0.54(65)			0.25(61)	0.751(181)
Nonresponders(n = 59)	0.05(3)	0.44(26)	0.51(30)			0.27(32)	0.73(86)
Taq1D 1 (rs 1800498)	D1D1	D1D2	D2D2	6.14	0.046*	D1	D2	0.65	0.42
Responders (n = 121)	0.15(18)	0.54(65)	0.31(38)			0.42(101)	0.58(141)
Nonresponders(n = 59)	0.03(2)	0.68(40)	0.29(17)			0.37(44)	0.63(74)
S311C (rs 1801028)	GG	GC	CC	0.99	0.61	G	C	0.26	0.61
Responders (n = 120)	0.79(95)	0.19(23)	0.02(2)			0.89(213)	0.11(27)
Nonresponders(n = 58)	0.81(47)	0.19(11)	(0)			0.90 (105)	0.10(11)
H313H2 (rs 6275)	TT	TC	CC	5.57	0.06	T	C	1.76	0.18
Responders (n = 122)	0.36(44)	0.41(50)	0.23(28)			0.57(138)	0.43(106)
Nonresponders(n = 59)	0.20(12)	0.58(34)	0.22(13)			0.49(58)	0.51(60)
Taq1A (rs 1800497)	A1A1	A1A2	A2A2	1.91	0.39	A1	A2	1.44	0.23
Responders (n = 121)	0.09(10)	0.42(51)	0.49(60)			0.29(71)	0.71(171)
Nonresponders(n = 59)	0.08(5)	0.53(31)	0.39(23)			0.35(41)	0.65(74)

¹Taq1D recessive model (D1D1vs D1D2 +D2D2) P = 0.023, Odds = 4.98, CI = 1.115 to 22.25

²H313H dominant model (TT Vs TC+CC) P = 0.0490, Odds = 0.490, CI = 0.2394 to 1.004