Table 2.
QTL for papilloma multiplicity
| total | female | male | |||||||||
| Number of papillomas c) | |||||||||||
| Marker | Map location a) | LRS | P-value b) | FF (Number of animals) | FP (Number of animals) | LRS | P-value b) | LRS | P-value b) | ||
| Chromosome1 | |||||||||||
| D1Mit18 | 21.4 | 7.4 | 0.00671* | 6.33 ± 0.96 | (103) | 3.37 ± 0.56 | (104) | 8.9 | 0.00288* | 0.9 | >0.01 |
| D1Mit284 | 35.6 | 6.8 | 0.00924 | 9.4 | 0.00219* | 0.9 | >0.01 | ||||
| D1Mit10 | 44.1 | 6.0 | >0.01 | 8.4 | 0.00383* | 0.7 | >0.01 | ||||
| Chromosome2 | |||||||||||
| D2Mit484 | 50 | 1.7 | >0.01 | 8.1 | 0.00445* | 0.2 | >0.01 | ||||
| D2Mit401 | 58.1 | 5.2 | >0.01 | 8.9 | 0.00289* | 0.5 | >0.01 | ||||
| D2Mit423 | 63.7 | 3.2 | >0.01 | 8.8 | 0.00308* | 0.0 | >0.01 | ||||
| Chromosome3 | |||||||||||
| D3mit40 | 36.1 | 7.6 | 0.0058* | 6.39 ± 0.94 | (109) | 3.19 ± 0.54 | (98) | 3.6 | >0.01 | 2.8 | >0.01 |
| Chromosome4 | |||||||||||
| D4Mit235 | 3.3 | 7.4 | 0.00648* | 6.56 ± 0.98 | (98) | 3.33 ± 0.57 | (110) | 4.1 | >0.01 | ||
| D4Mit93 | 16.1 | 11.0 | 0.00092* | 6.55 ± 0.94 | (99) | 3.31 ± 0.60 | (109) | 10.4 | 0.00123* | 3.2 | >0.01 |
| D4Mit111 | 22.1 | 12.5 | 0.00041* | 6.57 ± 0.94 | (99) | 3.29 ± 0.61 | (109) | 8.8 | 0.00354* | 4.8 | >0.01 |
| D4Mit26 | 36.3 | 34.4 | <0.00001*** | 7.94 ± 1.05 | (95) | 2.11 ± 0.39 | (109) | 16.5 | 0.00005** | 18.7 | 0.00002** |
| D4Mit167 | 40 | 34.2 | <0.00001*** | 7.82 ± 1.01 | (100) | 2.11 ± 0.39 | (108) | 21.5 | <0.00001*** | 15.0 | 0.00011** |
| D4Mit308 | 51.9 | 19.9 | 0.00001** | 6.72 ± 0.86 | (100) | 3.12 ± 0.69 | (108) | 11.6 | 0.00067* | 10.1 | 0.00147* |
| Chromosome11 | |||||||||||
| D11Mit339 | 33.8 | 8.3 | 0.00388* | 6.36 ± 0.92 | (99) | 3.48 ± 0.65 | (109) | 3.3 | >0.01 | 5.3 | >0.01 |
| Chromosome12 | |||||||||||
| D12Mit283 | 9.4 | 7.8 | 0.00534* | 6.24 ± 0.92 | (107) | 3.39 ± 0.60 | (101) | 2.5 | >0.01 | 4.6 | >0.01 |
| D12Mit153 | 15.1 | 7.0 | 0.0081* | 6.25 ± 0.93 | (105) | 3.44 ± 0.60 | (102) | 3.0 | >0.01 | 3.3 | >0.01 |
| Chromosome14 | |||||||||||
| D14Mit257 | 24.6 | 0.6 | >0.01 | 9.4 | 0.00222* | ||||||
| D14Mit203 | 44.1 | 8.4 | 0.00382* | 6.18 ± 0.89 | (100) | 3.63 ± 0.68 | (108) | 1.8 | >0.01 | 5.9 | >0.01 |
| D14Mit193 | 48.3 | 12.3 | 0.00046* | 6.43 ± 0.88 | (103) | 3.31 ± 0.67 | (105) | 1.8 | >0.01 | 11.0 | 0.00089* |
| D14Mit195 | 60.3 | 8.0 | 0.00465* | 5.96 ± 0.78 | (107) | 3.68 ± 0.81 | (101) | 1.5 | >0.01 | 6.2 | >0.01 |
| D14Mit197 | 72.7 | 1.0 | >0.01 | 8.0 | 0.00475* | ||||||
| Chromosome15 | |||||||||||
| D15Mit15 | 64.9 | 3.4 | >0.01 | 1.7 | >0.01 | 10.6 | 0.0011* | ||||
| D15Mit161 | 68.8 | 4.8 | >0.01 | 0.2 | >0.01 | 9.1 | 0.0026* | ||||
a) cM from the centrosome
b) P-value for the association at each locus
c) Data are shown as mean ± SEM.
Values in parenthesis are number of samples.
* Suggestive linkage
** Significant linkage
*** Highly Significant linkage