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. 2007 May 4;93(5):1758–1767. doi: 10.1529/biophysj.107.108209

TABLE 1.

Comparison of DNA detection sensitivity by gel electrophoresis and by AFM

Gel Electrophoresis AFM
Minimum amount of DNA ∼400 pg per lane (67) ∼1 pg (total)
Sensitivity ∼25 pg per band (67), (equivalent to 8.5 × 106 pUC18 molecules) Single molecules